Your body already has a built-in weight loss system that works like Wegovy, Ozempic and Mounjaro – food and your gut microbiome

Weight loss and diabetes drugs target regulatory pathways involved in metabolism that the microbes in your gut and certain molecules from food already play a key role in regulating.

By: Christopher Damman, University of Washington, The Conversation

Outlets: The Conversation

Published: April 26, 2026

Words: 1,039

Last Updated: 3 months ago


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By Christopher Damman, University of Washington

Wegovy, Ozempic and Mounjaro are weight loss and diabetes drugs that have made quite a splash in health news. They target regulatory pathways involved in both obesity and diabetes and are widely considered breakthroughs for weight loss and blood sugar control.

But do these drugs point toward a root cause of metabolic disease? What inspired their development in the first place?

It turns out your …

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