You’ve reached your weight loss goal on GLP-1 medications – what now?

Due to the body’s natural tendency to restore its former weight, many people regain their lost weight when they stop using GLP-1 drugs.

By: Amy J. Sheer, University of Florida, The Conversation

Outlets: The Conversation

Published: February 5, 2026

Words: 1,470

Last Updated: 1 month, 1 week ago

By Amy J. Sheer, University of Florida

GLP-1 drugs have ushered in a new era in weight loss.

In just a few years, medications such as semaglutide and tirzepatide, known by the brand names Ozempic, Wegovy, Mounjaro and Zepbound, have gone from niche diabetes treatments to household names, reshaping how America thinks about weight loss.

A November 2025 Kaiser Family Foundation poll found that 1 in 8 U.S. adults have tried …

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